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About GHK-Cu A naturally occurring copper-binding tripeptide composed of glycine, histidine, and lysine studied extensively in controlled laboratory environments

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In a nonclinical study using a rat model of renal impairment, in vivo ureteral imaging was successfully performed after pudexacianinium administration [15]

Access this article Similar content being viewed by others Data availability The data supporting this study's findings are available in the Open Science Framework at Abbreviations ASD: Antiseizure drugs AUC: Area under the curve BOD: Biochemical oxygen demand incubator CEUA: Ethics Committee for animal use CONCEA: Conselho Nacional de Controle de Experimentao Animal dpf: Days post-fertilization DZP: Diazepam GABA: Gamma-aminobutyric acid GABA A : Gamma-aminobutyric acid type A receptor Grm2 : Glutamate metabotropic receptor 2 gene GSH: Glutathione ALC: Acetyl-l-carnitine MDA: Malondialdehyde mGlu2: Metabotropic glutamate type 2 receptors mGluRs: Extra-synaptic metabotropic receptors NAC: N -Acetylcysteine PTZ: Pentylenetetrazole UFRGS: Universidade Federal do Rio Grande do Sul References Falco-Walter J

Calada D, Vianello D, Giampieri E, Sala C, Castellani G, de Graaf A et al (2014) The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: a systems biology approach

doi: 10.1038/s41563-019-0462-9 207 FurusawaYObataYFukudaSEndoTANakatoGTakahashiDet al