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Recent hypotheses suggest that GIP induces appetite suppression through independent receptors in the brain, mitigates gastrointestinal side effects of GLP-1 action, and prevents desensitization of GLP-1 receptors, thereby acting as a biased GLP-1RA [87]

Free radicals are molecules that have an odd number of electrons, making them unstable

Gabbay V, Klein RG, Katz Y, Mendoza S, Guttman LE, Alonso CM, et al

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Deficient glutamate clearance, usually associated with downregulation of EAAT transporters is one of the primary mechanisms of glutamate excitotoxicity leading to neuronal death (see Table 2 and the previous section)

During discontinuation, a family member or friend is also great to have as part of your support system to help deal with the emotional stress of stopping the medication