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This indicated enhanced ferroptosis in fibroblast-like synoviocytes (FLSs) by downregulating PI3K-AKT-ERK1/2 signaling pathway and the activation of the P53 pathway which collectively contributed to reduced cell proliferation, migration, and invasion of FLSs

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doi:10.1080/01480545.2018.1485687

Fruits, vegetables, nuts and whole grains are rich in nutrients that support your bodys defenses, including: Vitamin C (found in citrus and bell peppers) Vitamin E (found in nuts and seeds) Selenium and zinc (found in seafood, eggs and legumes) Plant compounds like flavonoids and polyphenols (found in colorful produce, teas and spices) Together, these nutrients help your body recover from stress, fight inflammation and stay resilient.[12] The problem comes when your bodys defense system cant keep up, either because of poor nutrition, aging, chronic stress or exposure to toxins

Nat Rev Immunol 20:5570 Chen G, Kroemer G, Kepp O (2020) Mitophagy: an emerging role in aging and age-associated diseases

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