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On a therapeutic note, some microbiota-targeted treatments have reduced protein aggregates in models: long-term broad-spectrum antibiotics reduced A deposition and microglial reactivity in an AD mouse model, and recolonization with a simplified microbiota reversed some of these effects, indicating that specific microbial communities can either exacerbate or ameliorate protopathic cascades [102]

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Thus, vCD44BP affects the generation of effector cells, suggesting that CD8 T cell priming is impaired when vCD44BP interferes with CD44-mediated functions

If you determine that you have a mycotoxin issue, the first step is to either get out of the moldy environment or have it professionally remediated

Cell 107 , 667677 (2001)