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To date, only limited states of the LP complexes from the nsNSVs have been reported, including the polymerases of VSV and RABV from the rhabdovirus family in the initiation state 26,28 , the polymerases of PIV3, PIV5, MuV and NDV from the paramyxovirus family in the post- or non-initiation state 26,27,28,29 , the polymerases of RSV and HMPV from the human metapneumovirus family as well as the polymerases of EBOV and MARV from the filovirus family in the elongation state 8,32,33,34 (Fig