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These changes reduce the capacity to recognize and eliminate ectopic endometrial cells and thereby facilitate their abnormal adhesion, survival, and implantation outside the uterine cavity (Vassilaki et al., 2025)

The integrants of this complex include ECM and its degrading enzymes, vascular endothelial cells, immunological cells, tumor cells, and inflammatory and growth factors

Higher intracellular MTX-PGs were associated with improved clinical responses and inter-individual variations in MTX-PG levels were shown to be at least partly (20%) explained by age, baseline erythrocyte-folate, a single nucleotide polymorphism in the gene for folylpolyglutamate synthetase, and MTX dose [41]

Colloids Surf B Biointerfaces 102:822832

Introduction Senescence is a cell-fate decision that is triggered in response to many different stressors including genotoxic stress, telomere attrition/damage, oncogene activation, and mitochondrial dysfunction (Herranz and Gil, 2018)

Shang S, Liu J, Hua F