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Disparities in the expression of ferroptosis-related genes between normal individuals and PD patients, especially in the SN region, underscore the potential for developing novel treatments that regulate ferroptosis to address the mechanisms of dopaminergic neuron degeneration in PD (see Figure 3)

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Additionally, CerS6 interacts with the sequestosome 1 protein, impairing mitophagy and contributing to mitochondrial dysfunction (Xu et al., 2024)

The Cancer antigen 19-9/GGT ratio serves as an independent prognostic predictor following radical resection in ampulla carcinoma (146)