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Furthermore, the antioxidant and anti-inflammatory properties of BL may mitigate levodopa-induced free radical generation, potentially reducing therapeutic requirements in PD patients (Jayanti et al., 2021

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doi: 10.1186/1742-2094-11-98 69

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Agonist, Antagonist Binding and Modulation of Bitter Receptors In simple pharmacological terms an antagonist is a ligand that inhibits the biological response induced by an agonist and does not induce any response of its own, while a ligand that reduces the constitutive/basal activity of a GPCR is considered an inverse agonist

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