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Hemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesis

The main points are as follows: Physiological and metabolic differences: there are notable differences in bacterial genera proportions and immune responses between rats and humans

Although Nrf2 does not directly contribute to aerobic glycolysis, glucose uptake and glycolytic activity are stimulated under the sustained activation of the PI3KAkt signaling (Wieman et al., 2007), thereby increasing the supply of glycolytic intermediates

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