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doi: 10.7759/cureus.7352 14

Protocol [2] CCl 4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted

Consequently, the requisite calcium level is constrained to remain below 1.5 mmol/L to maintain normal muscle physiology, resulting in afflicted animals assuming a protracted recumbent posture (89)