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Mekanisme kerjanya yang utama adalah sebagai antioksidan yang berperan penting dalam melindungi sel dari kerusakan oksidatif akibat paparan radikal bebas

Considering the recent surveys that document much improved safety of kratom compared to the prescription or illicit opioids 83,93,94 , a further decrease of MORs G protein signaling efficacy of the key mediator of kratoms opioid-like effects, 7OH 17 , may lead to even safer compounds, and illustrates the potential importance of the present work

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While the results of the sleep duration were varied, the majority of subjects reported a decrease in the number of times awakened during the night

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