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209 And a significant increase in -aminobutyric acid (GABA) and agmatine levels, without changes in glutamate levels, was observed in the hippocampus of rats subjected to a KD for 15 days compared to rats on a normal rat chow diet

It is unlikely to determine a safe dose of Mucuna pruriens based on the available literature and trials

Funding This study was funded through research grants from the National Research Foundation, South Africa (UID: 123634 and 132595)

doi: 10.3389/fmed.2017.00227 68 WangDCWangWZhuBWangX

We detected significantly reduced XBP1 levels at both time points although the reduction in XBP1 levels was relatively less at the later point likely due to significant and progressive decline of XBP1 expression in -cells of wild-type NOD mice prior to diabetes onset 5,35