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Similarly, Mif gene disruption was associated with caspase-3 activation resulting in neuronal loss and increased infarct size after ischemic stroke, indicating a potential overall neuroprotective effect of MIF

Tefferi A, Fathima S, Abdelmagid M, Alsugair A, Aperna F, Rezasoltani M, Yousuf M, Natu A, Csizmar CM, Gurney M, Lasho TL, Finke CM, Kanagal-Shamanna R, Hammond D, Chien KS, Bazinet A, DiNardo CD, Kadia TM, Mangaonkar AA, Daver NG, Pardanani AD, Borthakur G , Zepeda-Mendoza CJ, Reichard KK, He R, Loghavi S, Passamonti F, Ravandi F, Sasaki K, Larson D, Garcia-Manero G, Onida F, Gangat N, Montalban-Bravo G, Patnaik MM

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Renal tubular metabolism reviewed in health and disease