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Hcy is commonly found in blood plasma in four different forms: circulates as free thiol (1%), remains disulfide-bound to plasma proteins such as albumin (7080%), and combines with other Hcy to form the dimer Hcy or combines with other thiols (2030%) [6]

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Although ES has proven beneficial for wound repair, the mechanisms of DW, optimal device selection, and dosing protocols require further exploration

It is important to note that, unlike other inhibitors used, indomethacin at 50 mol/L was significantly toxic to BV-2 cells according to the LDH and MTT cell viability assays (data not shown), which could also be partially responsible for its inhibitory effect on NO production at this high concentration