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As the disease progresses, additional brain regions involved in higher cognitive functions are affected, leading to more widespread cognitive and behavioral impairments ( 4 Biochemical and molecular mechanisms in PD Parkinsons disease is a chronic neurodegenerative disorder that is also progressive, similar to AD, and mainly affects the motor system, though non-motor symptoms are also prevalent

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Most glaucoma models focus on increasing IOP, employing various methods to either elevate episcleral venous pressure or enhance aqueous outflow resistance

A key symptom is a significant increase in heart rate when moving from lying to standing, leading to dizziness or even fainting