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159 In another study, oral intake of curcuminoid micelles capsules containing 20.1 mg curcumin, 3.9 mg demethoxycurcumin, and 0.5 mg bisdemethoxycurcumin was shown to be safe, well-tolerated, and enhanced the bioavailability of curcumin in healthy subjects

For IL-1 antibody blockade, mice were treated with 4 mg kg 1 IL-1 antibody or IgG (Bio X Cell, BE0246, BE0091) before adoptive transfer and the treatment was repeated twice a week

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The recombinant protein was tested and normalized to standard activity assays for growth of human pluripotent stem cells

This is consistent with another study which showed that Tanshinone IIA (Tan) inhibit atherosclerotic plaque formation in ApoE -/- mice and it is suggested that Tan regulates cholesterol metabolism by reducing the expression of SR-A, while further enhancing ABCA1 and ABCG1 expression in human THP-1 cells via activation of ERK/Nrf2/HO-1 pathway (Liu et al., 2014)

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