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Mirabegron, a beta3-adrenoceptor agonist, is currently under investigation as an alternative strategy to achieve weight loss by inducing browning of subcutaneous white adipose tissue and increasing energy expenditure

doi:10.4187/respcare.06965 68

25, 22442258.e2247

Since this SSE is associated with a loss of sensitivity and accuracy, the above-mentioned sample preparation methods describe compromises between the minimization of these matrix effects by removing matrix components during sample clean-up, and the ability to detect a broad spectrum of analytes with reasonable sample preparation efforts and adequate sensitivity

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Cognitive function was assessed with the Telephone Interview for Cognitive Status-modified (TICS-m) at one to three years of follow-up