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This sustained neuroinflammation further contributes to neuropathic pain by promoting neuronal hyperexcitability and impairing nerve regeneration (Komirishetty et al., 2016

CHARMM36 all-atom additive protein force field: validation based on comparison to NMR data

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Export of lactate, which requires the regulation of lactate transporters (MCTs), is beneficial for preventing intracellular acidification and maintaining a high rate of glycolysis