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These findings suggest microbiota metabolites may regulate synaptic developmental processes and influence microglia-mediated synaptic pruning, though their effects demonstrate bidirectional modulation

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This may relate to differences in study design, dosing, duration, and patient baseline characteristics

Furthermore, scRNA-seq analysis of MRI-localized biopsies showed that astrocyte-like glioma cells are relatively abundant at the infiltrated margin, where they may escape surgical resection (Levitin et al, 2019), and due to their quiescent state may be resistant to standard of care radiation and chemotherapy

No human data exist on tumour-related risk for BPC-157 in either direction