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The synthesis of these -glutamyl peptides by -GCS and GS appears more likely to occur when cells are under pathological conditions that feature a Cys deficiency (Figure 7)

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Adult male SpragueDawley rats (Harlan, Madison, WI, USA) were implanted with jugular vein catheters under 2% isoflurane anesthesia and some rats received femoral arterial catheters 15,78,79