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We further integrate emerging data on exercise modality-specific exerkine signatures and discuss their translational relevance, limitations, and safety considerations across different stages of DR

Devoid of the multi-layered smooth muscle and elastic fibers characteristic of normal vessels, these abnormal vessels not only fail to effectively alleviate hypoxia but exacerbate tissue edema through increased vascular leakage

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Methods 17 , 399404 (2020)

References Mendis, S., Puska, P., Norrving, B

Therefore, its necessary to found other potential drugs to depress ferroptosis in SCI and TBI