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Adequate intake of B vitamins lowers homocysteine concentrations, thereby improving cerebral vascular function and reducing secondary ischemic injury (157)

The study protocol was approved by the medical ethics committee of the Maastricht University Medical Center+, the Netherlands and was in line with the Helsinki Declaration of Human Rights (identifier: NL73600.068.20/METC 20033)

Carbamidomethylation of cysteine was set as fixed modification, and protein N-terminal acetylation and oxidation of methionine were set as variable modifications

Therefore, the treatment of tumors using silibinin may benefit from the characteristic to induce apoptosis of tumor cells