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The utilization of contemporary technologies and encapsulation methodologies has facilitated the development of an array of formulations of GA, encompassing nanoparticles, hydrogels, gels, inclusion complexes, microcapsules, nanoemulsions and liposomes

The cell morphology was evaluated using a fluorescence inverted microscope and the ROS levels were measured using flow cytometer (Beckman Instruments, NanJing, China)

These conditions may also coincide with nutritional deficiencies, particularly of cysteine and glycine, which are required for glutathione synthesis, further impairing the cycle and promoting diversion toward PGA production [70, 71]

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Selenocysteine is also known as the 21st amino acid in the genetic code and plays an important role in the enzymatic reduction of hydrogen peroxide and hydroperoxides (Handy and Loscalzo 2022

Combinatorial therapy in tumor microenvironment: where do we stand