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the volume of plasma cleared of the drug per unit time is unaltered

Through the generation of mice that were engineered to have the diphtheria receptor under the control of the CD64 gene, all myeloid cells were specifically targeted for ablation (i.e., deletion)

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In other neurocognitive disorders associated with documented FDG-PET brain hypometabolism, such as MCI and AD, patients present with a decline in their cognitive abilities ranging from subjective complaints to more objectively and clinically defined cognitive deficits