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Tumour heterogeneity, adaptive resistance mechanisms, and potential toxicity to normal tissues are key concerns

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HIV Med 17:89105 Young AC, Yiannoutsos CT, Hegde M, Lee E, Peterson J, Walter R, Price RW, Meyerhoff DJ, Spudich S (2014) Cerebral metabolite changes prior to and after antiretroviral therapy in primary HIV infection

Dark side of cytotoxic therapy: chemoradiation-induced cell death and tumor repopulation

IV sessions typically last between 45 minutes and several hours

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