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In summary, at first glance, these studies suggest antioxidant strategies are not effective in ALS, but this may reflect the specific unfavorable pharmacological properties of the antioxidants trialled so far

Bottom line: The efficacy of a supplement isn't just about the milligrams on the label

Outlook and challenges As the global population and food demand keep increasing fast, and yet the environment has been endangered worse and worse by water deficit and soil salinization, abiotic stress becomes one of the most harmful factors that limit the growth and productivity of crops worldwide

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New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose