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9,16,17,18 When mitochondria sustain irreparable damage, degradation pathways are activated to prevent the accumulation of dysfunctional organelles

In addition, it remains unclear whether K d-la and K ce can respond to dynamic changes of cellular glycolysis in a similar fashion as K l-la

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Neutrophils secrete several proteinases, including neutrophil elastase (NE), neutrophil cathepsin G, and neutrophil proteinase-3, which may contribute to parenchymal destruction and chronic mucus hypersecretion