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(4) PLC may cleave membrane PIP into other signaling molecules, such as inositol-1,4,5-trisphosphate (IP) and diacylglycerol (DAG)

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In vitro studies demonstrated that Epitalon induced telomerase and lengthened telomeres in human cell cultures, allowing cells to continue dividing beyond the usual Hayflick limit [9]

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We assessed the survival of SK-MEL-103 either 3 or 5 days after siRNA transfection (Fig