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Moreover, AMPK can enhance Sirtuin-1, the NAD + -dependent deacetylases family member owning deacetylating activity (Wang et al., 2019), through increasing cellular nicotinamide adenine dinucleotide (NAD + ) levels

NADPH donates the electrons and becomes oxidized to NADP +

The mechanism of action of gene drugs is clear, and they can target eye cells with precise drug delivery and action, reducing side effects on other tissues and organs

Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH, Hung MC

AS, AD, MN, AA, FP, and SS were involved in manuscript preparation

Some literature describes hexarelin as a peptide GH secretagogue with potent GH-stimulating activity and reported cardioprotective actions. Hexarelin belongs in a complete GH secretagogue overview, but it should not dominate the article unless keyword data supports a dedicated comparison page