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Besides, it offers a bonus to your gut health, proving effective in the battle against digestive conditions

During development and progression of atherosclerosis, Nrf2 signaling modulates many physiological and pathophysiological processes, like regulation of lipid homeostasis, CD36 gene expression regulation, foam cell formation, macrophage polarization, immunity regulation (Th2 differentiation and inhibition of pro-inflammatory gene expression through NFB down-regulation), redox regulation and inflammation, improvement of endothelial dysfunction, as well as GSH synthesis and utilization (234245)

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Its concentration is more than 20-fold that in plasma and over 90% is in the reduced form

In fact, current pieces of evidence indicate that the antioxidant, anti-inflammatory and anti-apoptotic effects of DHA on metabolic diseases, including NAFLD, are mediated by resolvins (6365)

In vitro results are promising, showing induction of degranulation in FcR-expressing cells