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The dual role of NRF2 in colorectal cancer: targeting NRF2 as a potential therapeutic approach

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** Immediately before CRS grade II, this patient suffered CRS grade I for 5 days

J Biol Chem 291(36):18718

Downregulation of Parkin substrate mitofusin 2, another MAM tethering protein [62], or exogenous expression of Parkin was shown to rescue the disturbance of calcium homeostasis in the mutant fibroblasts [61]