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Another AD study, focused on targeting CD38, showed that CD38 knockdown in APP Swe mutation-expressing transgenic mice enhanced NAD + levels and reduced A plaques in brain extracts, mirrored by some improvement of cognitive performance 270,274

Abstract Molecular hydrogen gas (HG), administered through inhalation or as hydrogen-rich fluids (HRF), has demonstrated antioxidant, anti-inflammatory, antiapoptotic, cytoprotective, and beneficial mitochondrial effects in critical illness

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Similar neuropathological lesions involving the deposition of abnormal proteins also characterize other neurological disorders (Ross and Poirier, 2004), including AD (Kotzbauer et al., 2001

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[DOI] [PubMed] [Google Scholar] 166.Urban C.F