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doi: 10.1038/s41584-023-01062-9 291 BrosiusFCTuttleKRKretzlerM

These mice never have mature B or T cells in the circulation, whereas "leakiness" of SCED phenotype has been demonstrated which may cause variation in the transplantation efficiency

doi: 10.1016/j.bpg.2016.02.007

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However, deficiencies caused by impaired absorption, especially due to the lack of intrinsic factors (IFs), can lead to rapid deterioration within two to five years

Haugaard SB, Andersen O, Hansen BR, Orskov H, Andersen UB, Madsbad S, Iversen J, Flyvbjerg A: Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic human immunodeficiency virus-infected patients