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Ferroptosis, a recently discovered iron-dependent form of nonapoptotic cell death, has been associated with neurodegeneration and p53-mediated tumour suppression 28,29

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"The exoshell system is designed to be adapted different enzymes and prodrugs can be paired to tailor the therapy to specific cancer types and patient needs, while maintaining the oral delivery advantage that is so important for patient quality of life." The teams next steps include further investigation into the safety profile of necroptosis-based therapy, optimisation of the platform, and additional studies to assess its potential for future clinical translation

As a precautionary measure, however, women who are pregnant or breastfeeding and anyone suffering from a chronic disease should seek medical advice before starting to supplement with glutathione

BMC Pharmacol Toxicol 26 , 209 (2025)

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