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Among the tested derivatives, a compound known as A4 showed the most promising results, surpassing other curcumin derivatives in efficacy (456)

The helpful microbiota decreases while the pathogenic microbiome increases

Once released, GHK appeared to bind with Cu ions found in the blood and then stimulate the synthesis of decorin protein

PDAC typically exhibits increased mitochondrial fragmentation and elevated mitochondrial fission compared to normal tissues, indicating a heightened demand for mitochondrial quality control via mitophagy [14, 15]

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