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Within mitochondria, Complex and of the ETC are major sources of superoxide

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Eisner (Fellow of the American College of Emergency Physicians), Mikael Ryden (Karolinska Institutet), Heiichiro Udono (Okayama University), Naoto Hirano (University of Toronto), and Masahiko Endo (Hirosaki University) for their critical reading of the manuscript

Schep LJ, Slaughter RJ, Watts M, Mackenzie E, Gee P

A separate experiment showed that low concentrations of His that alone did not demetallate CuHSA, substantially increased the rate of the HSA demetallation by EDTA: three and sixfold increases were observed in the presence of 50 M and 100 M of His, respectively (Fig