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For example, stimulation of group II metabotropic glutamate receptor and blockade of group I metabotropic glutamate receptor could prevent relapse of cocaine, heroin, nicotine, and alcohol (8490)

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A polymorphism or variation in the sequence within an ER-response element located in the SELENOS promoter was found to result in reduced SELENOS promoter activity and gene expression (36)

The findings that abemaciclib enhanced tumor cell radiosensitivity, enhanced phosphorylation of gamma-H2AX in combination with radiation, and reduced phosphorylation of p-AKT and p-S6 attenuating PI3K/mTOR signaling as well as alleviating radiation-induced vasculogenesis qualifies it to be a multi-functional radiation modifier