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In addition, marked suppression of HCC cell growth was observed both in vitro and in vivo following treatment with a combination of wild-type p53-induced protein phosphatase 1 and PARP inhibitors (138)

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2022;63(2 Suppl 3):E255-E266

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CRISPR Therapeutics is pushing beyond rare diseases and into cardiometabolic territory with its in vivo editing platformdebuting first-in-human data for CTX310 (targeting ANGPTL3) and preclinical results for CTX340 (targeting AGT) at AHA 2025