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In comparison to the wild type mice, APP/PS1 mice experienced significant synaptic loss as well as a reduction in the number of neuronal cells in the cerebral cortex

The reason for the contradictory results in the in vitro experiments was probably the difference in the severity of the oxidation stress

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Preclinical Model Research : Referenced in rodent research settings, particularly for investigating functional outcomes in ischemia/stroke-related models (for research use only)