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During the recruitment appointment and subsequent follow-up appointments at six and twelve months, the clinical status and mental health of all volunteers were evaluated, peripheral blood samples were collected, 45 plasma biomarkers (cytokines, chemokines, and growth factors) were assessed, and a comprehensive investigation was conducted using neuropsychological and ophthalmological tests, PET-CT, and magnetic resonance neuroimaging

The scale of its clinical program, the magnitude of its effects, and its proven cardiovascular benefit represent a genuine step-change in what pharmacotherapy for obesity can achieve

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Professional guidance helps navigate these individual differences while maximizing therapeutic benefits.