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AAV-PHP.B-mediated global-scale expression in the mouse nervous system enables GBA1 gene therapy for wide protection from synucleinopathy

(5188:) Pyruvate kinase isozymes R/L (R-type/L-type pyruvate kinase) (Redcell/liver pyruvate kinase) (Pyruvate kinase 1)

doi: 10.1016/j.cell.2013.12.010 138 YangW.DengW.ZengJ.RenS.AliM

Abrupt increase in the level of hydrogen peroxide in leaves of winter wheat is caused by cold treatment

A deeper insight into these regulatory mechanisms will be essential to exploit emerging imaging capabilities for early diagnostics and, ultimately, for the development of truly causal and precision-based therapeutic approaches targeting neurovascular dysfunction

This suggests the MTHFR C677T mutation is a genetic risk factor of IS, and primary and secondary prevention should be initiated in a timely manner in population with this mutation