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The study included 141 patients with melanomas measuring 1 mm or less.[4][Level of evidence A1] There was no statistically significant difference in 10-year DFS or OS between the two treatment groups

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Goldemberg DC, Thuler LCS, de Melo AC

Physiological and pathological oral mucosal melanin hyperpigmentations may be similar in appearance, and sometimes may be difficult to differentiate even on the basis of history and microscopical features

Wevers KP, Hoekstra HJ

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