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Critically, lactate exhibits concentration-dependent duality: at 5 mM, it induces acidosis, inactivates pH-sensitive enzymes, and activates apoptotic signaling pathways [135] (Fig

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The difference between liposomal and nanoemulsion technology in pharmaceuticals lies in their structural approachliposomes rely on phospholipid bilayers, while nanoemulsions use surfactant-stabilized droplets, impacting their suitability for specific drugs

It has been observed that amyloid peptide is responsible for hydrogen peroxide accumulation within the cultures of neuroblastoma and hippocampal neurons [111, 112] probably by the direct binding of amyloid to catalase leading to decreased enzyme activities [26]

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Neurons grown on glass coverslips were transferred to a recording chamber of an upright microscope and continuously superfused with the extracellular medium (in the presence or absence of MgSO4, according to the experimental condition)