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Modified GRF 1-29 specifically aims to increase the amplitude of growth hormone pulses, resulting in more significant growth hormone release over time

Diagnosis typically involves an electrocardiogram (ECG), a Holter monitor (a portable ECG worn for 24-48 hours), or other cardiac tests

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Endothelial Differentiation hiPSCs were grown to approximately 50-70% confluent and differentiated according to an adapted version of a protocol previously described (Patsch et al., 2015)

Peptide: As used herein, peptide is less than or equal to 50 amino acids long, e.g., about 5, 10, 15, 20, 25, 30, 35, 40, 45, or 50 amino acids long

In LX-2 and GIST-T1 cells, both rhIGF1 and SB415286 increased KITLG mRNA (Figure 4F, H), although SB415286 was more effective in LX-2 cells and IGF1 had a greater effect in GIST-T1 cells