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202 Examining the brains of cognitively normal older-age subjects has revealed that adherence to a Mediterranean-like dietary pattern is associated with reduced -amyloid accumulation

Another study revealed that treatment with either MPP+ or 6-OHDA induced the changing of UPR proteins such as expression of BIP and CHOP, and phosphorylation of PERK and eIF2, while relieving ER stress with salubrinal, a selective inhibitor of eIF2 dephosphorylation, attenuated mitochondrial toxin-induced cell death [66]

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Peptide fragments may provide neoepitopes that are ready accessible to the immune system without need for classical intracellular processing by antigen presenting cells