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10.3748/wjg.v24.i47.5366 5 AnsariD.AnsariD.AnderssonR.Andrn-Sandberg

Rebound hunger occurs with appetite-suppressing medications when the brains hunger-regulating neurons, which have been pharmacologically suppressed, suddenly regain activity upon drug cessation

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The components play real roles in liver fat metabolism but no large well-designed randomised trial has demonstrated clinically meaningful weight loss from MIC shots