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These findings call for further studies that corroborate this possible relationship and evaluate the interrelationship between HSV-1 and neurodegeneration, assessing for example how neurodegeneration affects viral reactivation in the brain and the corresponding underlying molecular mechanisms

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doi: 10.1038/s41598-019-39060-1 94 Ortega-HernandezODShoenfeldY

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NEW RECOMMENDATIONS The ACIP now recommends that healthy adults 50 years old, including those who have already received Zostavax , be vaccinated with two doses of Shingrix (2-6 months apart).10 The committee voted that Shingrix is preferred over Zostavax for herpes zoster prevention