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102 (Suppl 4), 139146 (1994)

Mechanistically, G3BP1, an SG core protein, directly interacts with ferritin light chain in an IR/TMZ-induced G3BP1 methionine-333 oxidation-dependent manner

It has also been shown to help maintain the cellular mitochondria, the powerhouse portion of the cell where nutrients are converted to energy, within brain cells

Sequences were filtered to remove mitochondrial, ribosomal RNA and tRNA sequences with Bowtie2(v 2.2.9)

They do not measure medication strength

This combined approach addresses both the acute oxidative insult and the underlying metabolic capacity and resilience of auditory cells, offering a promising, multi-faceted therapeutic avenue for preventing noise-induced hearing loss and its frequent sequela, tinnitus, by safeguarding the energetic and redox homeostasis of the auditory system see in Figure 2 -