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Polyphenol oxidase (PPO) activity Finally, PPO activity was analyzed which was 2.330.04 nM min -1 g -1 FW in the control callus (Fig

However, Xc-system inhibition results in glutathione and Cys deficiencies, triggering ferroptosis ( GPX4, also known as phospholipid hydroperoxide glutathione peroxidase, consists of approximately 170 amino acids and has a molecular weight of about 19 kDa

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447,448,449,450 Upregulated autophagy in macrophages enhances the production of pro-inflammatory cytokines such as IL-6 and TNF-, while autophagy deficiency promotes exaggerated inflammasome activation, as demonstrated by ATG16L1 ablation increasing IL-1 and IL-18 secretion

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Dysregulated choline, methionine, and aromatic amino acid metabolism in patients with wilson disease: exploratory metabolomic profiling and implications for hepatic and neurologic phenotypes