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V., Borelli, A

It can transmit diverse zoonotic pathogens, including Babesia spp., Rickettsia spp., Crimean-Congo hemorrhagic fever virus and human typhus fever virus [6]

Additionally, the accumulation of ROS can disrupt mitochondrial function, resulting in a loss of mitochondrial membrane potential and the release of pro-apoptotic factors like cytochrome c and AIF into the cytosol, which activates the caspase cascade and causes DNA fragmentation, leading to apoptosis

faecalis genome-scale metabolic model (GSMM) published in 2015 (41), which was recently expanded and curated (42)

For example, the variant 677T is most commonly associated with cerebral vascular accident (stroke), elevated homocysteine, cardiovascular disease risk, peripheral neuropathy, deep vein thrombosis, early-onset heart disease, stillbirth, neuro-tube defect, cleft lip, and preeclampsia